Sequence and structure ofTetrahymenaSRP RNA
نویسندگان
چکیده
منابع مشابه
RNA Sequence to Structure Mapping
Motivated by the observation, that RNA folding gives rise to extended neutral networks in sequence space, concepts of random graph theory are applied to build a model of RNA sequence to structure mappings. This model allows to investigate generic properties of sequence-structure relations as well as the effect of neutrality. The random mapping construction is based on two tunable parameters. Th...
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The secondary structures of the RNAs from the signal recognition particle, termed SRP-RNA, were derived buy comparative analyses of an alignment of 39 sequences. The models are minimal in that only base pairs are included for which there is comparative evidence. The structures represent refinements of earlier versions and include a new short helix.
متن کاملSequence and structure of Tetrahymena SRP RNA.
Signal recognition particle (SRP) is a ribonucleoprotein required for targeting of presecretory proteins to the endoplasmic reticulum (reviewed in 1). The well-studied canine particle is composed of six polypeptides and one RNA molecule often referred to as 7SL. We report here the sequence and proposed structure of an SRP RNA homolog from Tetrahymena, initially identified on the basis of size a...
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Ribonuclic acid (RNA) enjoys increasing interest in molecular biology; despite this interest fundamental algorithms are lacking, e.g. for identifying local motifs. As proteins, RNA molecules have a distinctive structure. Therefore, in addition to sequence information, structure plays an important part in assessing the similarity of RNAs. Furthermore, common sequence-structure features in two or...
متن کاملLocal RNA structure alignment with incomplete sequence
MOTIVATION Accuracy of automated structural RNA alignment is improved by using models that consider not only primary sequence but also secondary structure information. However, current RNA structural alignment approaches tend to perform poorly on incomplete sequence fragments, such as single reads from metagenomic environmental surveys, because nucleotides that are expected to be base paired ar...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1991
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/19.8.1942